Better treatment for stroke
The INTERACT trials were designed to establish the effects of early intensive blood pressure (BP) lowering on recovery for patients with acute intracerebral haemorrhage (ICH), the most serious form of acute stroke.
The main study, INTERACT2, involved 2839 participants from 21 countries to show that early intensive BP treatment was safe and improved chances of recovery with better physical function. It resulted in a shift in clinical guidelines recommending better control of BP in ICH.
Interact3 was recently launched and aims to establish the effects of a ‘care bundle’ involving the early use of intensive BP lowering, control of glucose and fever, and correction of anticoagulation, as compared to routine care.