John Chalmers AC's Publications

• Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial

  Journal articles

  2021

  The Lancet

• Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control

  Journal articles

  2021

  Diabetologia

• Disparities between Asian and Non-Asian Thrombolyzed Acute Ischemic Stroke Patients in the Enhanced Control of Hypertension and Thrombolysis Stroke Trial

  Journal articles

  2021

  Cerebrovascular Diseases

• Smoking influences outcome in patients who had thrombolysed ischaemic stroke: The ENCHANTED study

  Journal articles

  2021

  Stroke and Vascular Neurology

• Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials

  Journal articles

  2021

  Frontiers in Neurology

• Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials

  Journal articles

  2021

  Journal of hypertension

• Sex differences in risk factors for cognitive decline and dementia, including death as a competing risk, in individuals with diabetes: Results from the ADVANCE trial

  Journal articles

  2021

  Diabetes, Obesity and Metabolism

• Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis

  Journal articles

  2021

  PLoS Medicine

• Variability in estimated glomerular filtration rate and the risk of major clinical outcomes in diabetes: Post hoc analysis from the ADVANCE trial

  Journal articles

  2021

  Diabetes, Obesity and Metabolism

• The comparative effects of intensive glucose lowering in diabetes patients aged below or above 65 years: Results from the ADVANCE trial

  Journal articles

  2021

  Diabetes, Obesity and Metabolism

• Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis

  Journal articles

  2021

  The Lancet

• Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis

  Journal articles

  2021

  The Lancet Oncology

• Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

  Journal articles

  2021

  Kidney International

• Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial

  Journal articles

  2021

  Neurology

• Low Dose versus Standard Dose Alteplase in Acute Lacunar Ischemic Stroke.

  Journal articles

  2021

  STROKE

• Intensive versus guideline-recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: The ENCHANTED trial

  Journal articles

  2021

  European Journal of Neurology

• Economic Evaluation of a New Polygenic Risk Score to Predict Nephropathy in Adult Patients With Type 2 Diabetes

  Journal articles

  2021

  Canadian Journal of Diabetes

• Erratum. Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications. Diabetes Care 2021;44:390-398.

  Journal articles

  2021

  Diabetes Care

• Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications

  Journal articles

  2021

  Diabetes Care

• Associations of an Abnormal Physiological Score With Outcomes in Acute Intracerebral Hemorrhage: INTERACT2 Study

  Journal articles

  2021

  Stroke