01873nas a2200241   4500000000100000008004100001100001900042700001700061700001300078700001800091700001600109700001400125700001500139700001600154700001200170700001100182700001300193245010200206300000900308490000600317520129400323022001401617       2017                            d1 aAnderson Craig1 aHuang Yining1 aLiu Ming1 aWang Ji-Guang1 aSun Weiping1 aXian Ying1 aZhu Sainan1 aJia Zhirong1 aLiu Ran1 aLi Fan1 aWei Jade00aAssociation of body mass index with mortality and functional outcome after acute ischemic stroke.  a25070 v73 a<p>
The relation between obesity and stroke outcome has been disputed. This study was aimed to determine the association of body mass index (BMI) with mortality and functional outcome in patients with acute ischemic stroke. Data were from a national, multi-centre, prospective, hospital-based register: the ChinaQUEST (Quality Evaluation of Stroke Care and Treatment) study. Of 4782 acute ischemic stroke patients, 282 were underweight (BMI &lt; 18.5 kg/m(2)), 2306 were normal-weight (BMI 18.5 to &lt; 24 kg/m(2)), 1677 were overweight (BMI 24 to &lt;28 kg/m(2)) and 517 were obese (BMI ≥ 28 kg/m(2)). The risks of death at 12 months and death or high dependency at 3 and 12 months in overweight (HR: 0.97, 95% CI: 0.78-1.20; OR: 0.93, 95% CI: 0.80-1.09; OR: 0.95, 95% CI: 0.81-1.12) and obese patients (HR: 1.07, 95% CI: 0.78-1.48; OR: 0.96, 95% CI: 0.75-1.22; OR: 1.06, 95% CI: 0.83-1.35) did not differ from normal-weight patients significantly after adjusting for baseline characteristics. Underweight patients had significantly increased risks of these three outcomes. In ischemic stroke patients, being overweight or obese was not associated with decreased mortality or better functional recovery but being underweight predicted unfavourable outcomes.
</p>
  a2045-2322